Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10380.072 | 0.9916 | 0.9884 | 1.4455 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10380.072 | 1.0788 | 1.1078 | 1.4455 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10380.072 | 1.0113 | 1.0156 | 1.4455 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10380.072 | 1.0228 | 1.0314 | 1.4455 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10380.072 | 0.9943 | 0.9921 | 1.4455 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10380.072 | 0.9197 | 0.8875 | 1.4455 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10380.072 | 0.9389 | 0.9147 | 1.4455 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10816.072 | 0.9628 | 0.9059 | 0.7870 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10816.072 | 1.0499 | 1.1277 | 0.7870 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10816.072 | 1.0006 | 1.0014 | 0.7870 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10816.072 | 1.0723 | 1.1856 | 0.7870 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10816.072 | 1.0051 | 1.0129 | 0.7870 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10816.072 | 1.0209 | 1.0532 | 0.7870 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10816.072 | 0.8542 | 0.6370 | 0.7870 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10816.072 | 0.7885 | 0.4787 | 0.7870 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10816.072 | 0.0277 | -0.9790 | 0.7870 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7485.072 | 1.0614 | 1.0346 | 3.4800 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7485.072 | 0.9929 | 0.9959 | 3.4800 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7485.072 | 0.9755 | 0.9858 | 3.4800 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7485.072 | 1.0735 | 1.0412 | 3.4800 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7485.072 | 1.1517 | 1.0828 | 3.4800 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7485.072 | 1.1783 | 1.0966 | 3.4800 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7485.072 | 0.9460 | 0.9683 | 3.4800 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7485.072 | 0.4091 | 0.5470 | 3.4800 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7485.072 | 0.1786 | 0.2192 | 3.4800 |