Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 11056.072 | 1.0572 | 1.0388 | 2.8988 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 11056.072 | 1.0016 | 1.0011 | 2.8988 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 11056.072 | 1.0010 | 1.0007 | 2.8988 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 11056.072 | 1.0410 | 1.0279 | 2.8988 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 11056.072 | 1.0052 | 1.0036 | 2.8988 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 11056.072 | 1.0563 | 1.0382 | 2.8988 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 11056.072 | 0.7827 | 0.8379 | 2.8988 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 11056.072 | 0.3693 | 0.4184 | 2.8988 | |
| MCF 10A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 11056.072 | 0.2978 | 0.3169 | 2.8988 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7486.072 | 1.0086 | 1.0158 | 1.0885 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7486.072 | 1.0963 | 1.1763 | 1.0885 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7486.072 | 0.9472 | 0.9028 | 1.0885 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7486.072 | 1.0848 | 1.1553 | 1.0885 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7486.072 | 1.1347 | 1.2461 | 1.0885 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7486.072 | 1.1710 | 1.3122 | 1.0885 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7486.072 | 1.3525 | 1.6393 | 1.0885 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7486.072 | 1.2652 | 1.4825 | 1.0885 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7486.072 | 1.0893 | 1.1636 | 1.0885 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 12254.072 | 1.0205 | 1.0210 | 1.9429 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 12254.072 | 1.0250 | 1.0256 | 1.9429 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 12254.072 | 0.9729 | 0.9719 | 1.9429 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 12254.072 | 0.9340 | 0.9309 | 1.9429 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 12254.072 | 0.9824 | 0.9818 | 1.9429 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 12254.072 | 1.2839 | 1.2746 | 1.9429 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 12254.072 | 1.2246 | 1.2198 | 1.9429 |