Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7472.072 | 1.2430 | 1.3879 | 1.2269 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7472.072 | 1.4122 | 1.6497 | 1.2269 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7472.072 | 1.2999 | 1.4768 | 1.2269 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7472.072 | 2.2183 | 2.8286 | 1.2269 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7472.072 | 1.2996 | 1.4763 | 1.2269 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10379.072 | 1.1177 | 1.1072 | 2.1304 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10379.072 | 1.0528 | 1.0489 | 2.1304 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10379.072 | 1.0608 | 1.0562 | 2.1304 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10379.072 | 1.0001 | 1.0001 | 2.1304 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10379.072 | 1.1252 | 1.1139 | 2.1304 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10379.072 | 1.0522 | 1.0483 | 2.1304 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10379.072 | 1.1562 | 1.1411 | 2.1304 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10379.072 | 0.9137 | 0.9170 | 2.1304 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10379.072 | 0.6584 | 0.6437 | 2.1304 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10694.072 | 0.9596 | 0.9627 | 2.1922 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10694.072 | 0.8825 | 0.8891 | 2.1922 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10694.072 | 0.9287 | 0.9337 | 2.1922 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10694.072 | 0.9301 | 0.9349 | 2.1922 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10694.072 | 0.9265 | 0.9316 | 2.1922 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10694.072 | 0.8845 | 0.8911 | 2.1922 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10694.072 | 1.0490 | 1.0442 | 2.1922 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10694.072 | 0.9019 | 0.9080 | 2.1922 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10694.072 | 0.1319 | -0.2061 | 2.1922 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10380.072 | 1.0462 | 1.0635 | 1.4455 | |
| LY2 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10380.072 | 1.0805 | 1.1101 | 1.4455 |