Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7470.073 | 1.0043 | 1.0070 | 1.2165 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7470.073 | 1.0139 | 1.0228 | 1.2165 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7470.073 | 0.7066 | 0.5033 | 1.2165 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10873.072 | 1.0316 | 1.0533 | 1.1824 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10873.072 | 1.0113 | 1.0191 | 1.1824 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10873.072 | 1.0432 | 1.0728 | 1.1824 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10873.072 | 1.0326 | 1.0550 | 1.1824 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10873.072 | 1.0150 | 1.0253 | 1.1824 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10873.072 | 1.0713 | 1.1199 | 1.1824 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10873.072 | 1.0306 | 1.0516 | 1.1824 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10873.072 | 0.9888 | 0.9810 | 1.1824 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10873.072 | 0.5491 | 0.2046 | 1.1824 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7471.072 | 1.0074 | 1.0067 | 2.2270 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7471.072 | 1.0147 | 1.0132 | 2.2270 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7471.072 | 1.0039 | 1.0035 | 2.2270 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7471.072 | 1.0244 | 1.0218 | 2.2270 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7471.072 | 1.0045 | 1.0040 | 2.2270 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7471.072 | 0.9604 | 0.9641 | 2.2270 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7471.072 | 1.0681 | 1.0600 | 2.2270 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7471.072 | 0.8657 | 0.8746 | 2.2270 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7471.072 | 0.0301 | -0.5854 | 2.2270 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7472.072 | 1.3399 | 1.5386 | 1.2269 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7472.072 | 1.0778 | 1.1259 | 1.2269 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7472.072 | 1.1555 | 1.2501 | 1.2269 | |
| Hs 578T | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7472.072 | 1.1602 | 1.2574 | 1.2269 |