Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7507.074 | 0.9609 | 0.9065 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7507.074 | 0.9609 | 0.9065 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7507.074 | 1.0492 | 1.1186 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7507.074 | 1.0492 | 1.1186 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7507.074 | 0.9313 | 0.8363 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7507.074 | 0.9313 | 0.8363 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7507.074 | 0.8755 | 0.7054 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7507.074 | 0.8755 | 0.7054 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7507.074 | 0.7580 | 0.4349 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7507.074 | 0.7580 | 0.4349 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7507.074 | 0.6589 | 0.2128 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7507.074 | 0.6589 | 0.2128 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7507.074 | 0.4294 | -0.2740 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7507.074 | 0.4294 | -0.2740 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7508.074 | 1.0454 | 1.1152 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7508.074 | 1.0454 | 1.1152 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7508.074 | 1.0130 | 1.0329 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7508.074 | 1.0130 | 1.0329 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7508.074 | 1.0199 | 1.0503 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7508.074 | 1.0199 | 1.0503 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7508.074 | 1.0429 | 1.1089 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7508.074 | 1.0429 | 1.1089 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7508.074 | 1.0226 | 1.0573 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7508.074 | 1.0226 | 1.0573 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7508.074 | 0.9778 | 0.9442 | 0.7924 |