Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7508.074 | 0.9778 | 0.9442 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7508.074 | 0.8597 | 0.6527 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7508.074 | 0.8597 | 0.6527 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7508.074 | 0.8009 | 0.5112 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7508.074 | 0.8009 | 0.5112 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7508.074 | 0.6744 | 0.2166 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7508.074 | 0.6744 | 0.2166 | 0.7924 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14767.203 | 0.9593 | 0.9206 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14767.203 | 0.9593 | 0.9206 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14767.203 | 0.9206 | 0.8449 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14767.203 | 0.9206 | 0.8449 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14767.203 | 0.9661 | 0.9338 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14767.203 | 0.9661 | 0.9338 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14767.203 | 0.5809 | 0.1774 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14767.203 | 0.5809 | 0.1774 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14767.203 | 0.2445 | -0.4936 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14767.203 | 0.2445 | -0.4936 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14767.203 | 0.2174 | -0.5485 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14767.203 | 0.2174 | -0.5485 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14767.203 | 0.1878 | -0.6085 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14767.203 | 0.1878 | -0.6085 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14767.203 | 0.1339 | -0.7185 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14767.203 | 0.1339 | -0.7185 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14767.203 | 0.0894 | -0.8101 | 1.0253 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14767.203 | 0.0894 | -0.8101 | 1.0253 |