Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7468.073 | 0.1150 | -0.5675 | 1.4124 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10418.072 | 1.0597 | 1.1083 | 1.1007 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10418.072 | 1.0161 | 1.0291 | 1.1007 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10418.072 | 0.9585 | 0.9245 | 1.1007 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10418.072 | 1.0409 | 1.0742 | 1.1007 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10418.072 | 0.9893 | 0.9805 | 1.1007 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10418.072 | 0.9897 | 0.9812 | 1.1007 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10418.072 | 1.0285 | 1.0517 | 1.1007 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10418.072 | 0.5712 | 0.2024 | 1.1007 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10418.072 | 0.1332 | -0.6797 | 1.1007 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10578.072 | 1.0147 | 1.0176 | 1.6597 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10578.072 | 0.9616 | 0.9534 | 1.6597 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10578.072 | 1.0158 | 1.0189 | 1.6597 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10578.072 | 0.9668 | 0.9597 | 1.6597 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10578.072 | 1.0159 | 1.0191 | 1.6597 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10578.072 | 0.9781 | 0.9735 | 1.6597 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10578.072 | 1.0042 | 1.0050 | 1.6597 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10578.072 | 0.7774 | 0.7185 | 1.6597 | |
| HCC38 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10578.072 | 0.0497 | -0.6724 | 1.6597 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7470.073 | 1.0089 | 1.0147 | 1.2165 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7470.073 | 0.9752 | 0.9591 | 1.2165 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7470.073 | 0.9734 | 0.9562 | 1.2165 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7470.073 | 0.9930 | 0.9884 | 1.2165 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7470.073 | 0.9947 | 0.9913 | 1.2165 | |
| HCC70 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7470.073 | 0.9784 | 0.9643 | 1.2165 |