Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7517.073 | 0.9557 | 0.9387 | 1.4542 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7517.073 | 0.9724 | 0.9618 | 1.4542 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7517.073 | 0.9442 | 0.9226 | 1.4542 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7517.073 | 0.9311 | 0.9043 | 1.4542 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7517.073 | 0.9208 | 0.8896 | 1.4542 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7517.073 | 0.9825 | 0.9759 | 1.4542 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7517.073 | 0.5038 | 0.2482 | 1.4542 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10644.072 | 1.0392 | 1.1554 | 0.5146 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10644.072 | 0.9803 | 0.9243 | 0.5146 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10644.072 | 0.9707 | 0.8876 | 0.5146 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10644.072 | 0.9572 | 0.8371 | 0.5146 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10644.072 | 1.0061 | 1.0236 | 0.5146 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10644.072 | 0.9188 | 0.6964 | 0.5146 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10644.072 | 0.9583 | 0.8412 | 0.5146 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10644.072 | 0.5171 | -0.4449 | 0.5146 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10644.072 | 0.1726 | -0.9342 | 0.5146 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10874.072 | 0.9618 | 0.9135 | 0.8811 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10874.072 | 1.0068 | 1.0155 | 0.8811 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10874.072 | 1.0200 | 1.0455 | 0.8811 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10874.072 | 0.9964 | 0.9918 | 0.8811 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10874.072 | 0.9466 | 0.8792 | 0.8811 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10874.072 | 1.0125 | 1.0283 | 0.8811 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10874.072 | 0.9031 | 0.7815 | 0.8811 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10874.072 | 0.7727 | 0.4925 | 0.8811 | |
| MX1 | Unknown | Unknown | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10874.072 | 0.0782 | -0.8891 | 0.8811 |