Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10938.072 | 1.3212 | 2.2854 | 0.5611 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10938.072 | 1.3529 | 2.4272 | 0.5611 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10938.072 | 1.2010 | 1.7718 | 0.5611 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10938.072 | 1.4119 | 2.6980 | 0.5611 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10938.072 | 1.1602 | 1.6063 | 0.5611 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7515.072 | 0.9781 | 0.9579 | 1.0390 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7515.072 | 0.8375 | 0.6861 | 1.0390 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7515.072 | 0.9565 | 0.9161 | 1.0390 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7515.072 | 0.9766 | 0.9549 | 1.0390 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7515.072 | 0.8716 | 0.7522 | 1.0390 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7515.072 | 0.8619 | 0.7335 | 1.0390 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7515.072 | 0.8964 | 0.8002 | 1.0390 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7515.072 | 0.9520 | 0.9075 | 1.0390 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7515.072 | 0.7760 | 0.5669 | 1.0390 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7516.072 | 0.9749 | 0.9611 | 1.2937 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7516.072 | 0.9416 | 0.9090 | 1.2937 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7516.072 | 0.9786 | 0.9669 | 1.2937 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7516.072 | 0.9763 | 0.9633 | 1.2937 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7516.072 | 0.9845 | 0.9760 | 1.2937 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7516.072 | 0.9416 | 0.9090 | 1.2937 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7516.072 | 0.9773 | 0.9647 | 1.2937 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7516.072 | 1.0021 | 1.0033 | 1.2937 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7516.072 | 0.6727 | 0.4721 | 1.2937 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7517.073 | 0.9687 | 0.9567 | 1.4542 | |
| MDA-MB-453 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7517.073 | 0.9592 | 0.9435 | 1.4542 |