Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15327.203 | 0.9027 | 0.7903 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15327.203 | 0.9027 | 0.7903 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15327.203 | 0.5402 | 0.0276 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15327.203 | 0.5402 | 0.0276 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15327.203 | 0.2227 | -0.6060 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15327.203 | 0.2227 | -0.6060 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15327.203 | 0.1452 | -0.7519 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15327.203 | 0.1452 | -0.7519 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15327.203 | 0.1198 | -0.7984 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15327.203 | 0.1198 | -0.7984 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15327.203 | 0.1092 | -0.8177 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15327.203 | 0.1092 | -0.8177 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15327.203 | 0.1153 | -0.8066 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15327.203 | 0.1153 | -0.8066 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15327.203 | 0.1250 | -0.7890 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15327.203 | 0.1250 | -0.7890 | 0.9247 | |
| SUM1315MO2 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7528.074 | 1.0157 | 1.0309 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7528.074 | 1.0157 | 1.0309 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7528.074 | 1.0433 | 1.0854 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7528.074 | 1.0433 | 1.0854 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7528.074 | 0.9925 | 0.9852 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7528.074 | 0.9925 | 0.9852 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7528.074 | 0.9434 | 0.8883 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7528.074 | 0.9434 | 0.8883 | 1.0143 | |
| SUM1315MO2 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7528.074 | 0.6238 | 0.2560 | 1.0143 |