Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7526.074 | 0.0672 | -0.6105 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7526.074 | 0.0690 | -0.6041 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7526.074 | 0.0690 | -0.6041 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7526.074 | 0.0845 | -0.5525 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7526.074 | 0.0845 | -0.5525 | 1.6506 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7527.074 | 1.0185 | 1.0193 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7527.074 | 1.0185 | 1.0193 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7527.074 | 0.9963 | 0.9962 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7527.074 | 0.9963 | 0.9962 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7527.074 | 0.9922 | 0.9919 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7527.074 | 0.9922 | 0.9919 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7527.074 | 0.3336 | 0.1278 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7527.074 | 0.3336 | 0.1278 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7527.074 | 0.1764 | -0.1913 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7527.074 | 0.1764 | -0.1913 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7527.074 | 0.1395 | -0.2845 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7527.074 | 0.1395 | -0.2845 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7527.074 | 0.0930 | -0.4209 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7527.074 | 0.0930 | -0.4209 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7527.074 | 0.0972 | -0.4074 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7527.074 | 0.0972 | -0.4074 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7527.074 | 0.1007 | -0.3964 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7527.074 | 0.1007 | -0.3964 | 1.9162 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15327.203 | 0.9658 | 0.9262 | 0.9247 | |
| SK-BR-3 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15327.203 | 0.9658 | 0.9262 | 0.9247 |