Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7530.074 | 0.9575 | 0.9590 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7530.074 | 0.5778 | 0.5396 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7530.074 | 0.5778 | 0.5396 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7530.074 | 0.0168 | -0.7156 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7530.074 | 0.0168 | -0.7156 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7530.074 | 0.0036 | -0.8643 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7530.074 | 0.0036 | -0.8643 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7530.074 | 0.0029 | -0.8760 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7530.074 | 0.0029 | -0.8760 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7530.074 | 0.0062 | -0.8232 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7530.074 | 0.0062 | -0.8232 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7530.074 | 0.0026 | -0.8823 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7530.074 | 0.0026 | -0.8823 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15330.203 | 0.9704 | 0.9537 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15330.203 | 0.9704 | 0.9537 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15330.203 | 0.9236 | 0.8799 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15330.203 | 0.9236 | 0.8799 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15330.203 | 0.6600 | 0.4470 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15330.203 | 0.6600 | 0.4470 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15330.203 | 0.1527 | -0.5375 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15330.203 | 0.1527 | -0.5375 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15330.203 | 0.1126 | -0.6351 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15330.203 | 0.1126 | -0.6351 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15330.203 | 0.1101 | -0.6414 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15330.203 | 0.1101 | -0.6414 | 1.2836 |