Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7531.073 | 1.1723 | 1.0932 | 3.4904 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7531.073 | 1.2575 | 1.1357 | 3.4904 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7531.073 | 1.0000 | 1.0000 | 3.4904 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7531.073 | 0.5464 | 0.6820 | 3.4904 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10520.072 | 1.2650 | 1.1448 | 3.3637 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10520.072 | 1.0715 | 1.0415 | 3.3637 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10520.072 | 0.8673 | 0.9171 | 3.3637 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10520.072 | 1.0581 | 1.0339 | 3.3637 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10520.072 | 1.1433 | 1.0812 | 3.3637 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10520.072 | 1.1672 | 1.0941 | 3.3637 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10520.072 | 1.0176 | 1.0104 | 3.3637 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10520.072 | 0.8039 | 0.8744 | 3.3637 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10520.072 | 0.0046 | -0.5968 | 3.3637 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 11057.072 | 1.0692 | 1.0335 | 4.0230 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 11057.072 | 1.0143 | 1.0071 | 4.0230 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 11057.072 | 1.0821 | 1.0396 | 4.0230 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 11057.072 | 1.0496 | 1.0242 | 4.0230 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 11057.072 | 1.0813 | 1.0392 | 4.0230 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 11057.072 | 1.0287 | 1.0141 | 4.0230 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 11057.072 | 0.9931 | 0.9966 | 4.0230 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 11057.072 | 0.9850 | 0.9925 | 4.0230 | |
| SUM159PT | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 11057.072 | 0.4731 | 0.6604 | 4.0230 | |
| SUM185PE | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 12269.072 | 0.7808 | 0.6053 | 1.1256 | |
| SUM185PE | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 12269.072 | 0.9356 | 0.8852 | 1.1256 | |
| SUM185PE | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 12269.072 | 0.6377 | 0.3410 | 1.1256 |