Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15330.203 | 0.0998 | -0.6680 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15330.203 | 0.0998 | -0.6680 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15330.203 | 0.0703 | -0.7472 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15330.203 | 0.0703 | -0.7472 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15330.203 | 0.0340 | -0.8564 | 1.2836 | |
| SUM149PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15330.203 | 0.0340 | -0.8564 | 1.2836 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7531.074 | 1.1101 | 1.0653 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7531.074 | 1.1101 | 1.0653 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7531.074 | 1.0203 | 1.0124 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7531.074 | 1.0203 | 1.0124 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7531.074 | 0.8654 | 0.9130 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7531.074 | 0.8654 | 0.9130 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7531.074 | 0.4061 | 0.5155 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7531.074 | 0.4061 | 0.5155 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7531.074 | 0.0419 | -0.2470 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7531.074 | 0.0419 | -0.2470 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7531.074 | 0.0006 | -0.7953 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7531.074 | 0.0006 | -0.7953 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7531.074 | 0.0006 | -0.7953 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7531.074 | 0.0006 | -0.7953 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7531.074 | 0.0006 | -0.7953 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7531.074 | 0.0006 | -0.7953 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7531.074 | 0.0006 | -0.7953 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7531.074 | 0.0006 | -0.7953 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14921.203 | 0.9499 | 0.9669 | 3.0799 |