Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7877.042 | 0.5352 | -0.6795 | 0.3414 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7877.042 | 0.0804 | -0.9988 | 0.3414 | |
| MDA-MB-157 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7879.018 | 1.0233 | 1.0259 | 1.7910 | |
| MDA-MB-157 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7879.018 | 1.0356 | 1.0394 | 1.7910 | |
| MDA-MB-157 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7879.018 | 1.0597 | 1.0658 | 1.7910 | |
| MDA-MB-157 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7879.018 | 0.3766 | 0.1593 | 1.7910 | |
| MDA-MB-157 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7879.018 | 0.1076 | -0.4240 | 1.7910 | |
| MDA-MB-157 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7879.018 | 0.1075 | -0.4242 | 1.7910 | |
| MDA-MB-157 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7879.018 | 0.0994 | -0.4489 | 1.7910 | |
| MDA-MB-157 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7879.018 | 0.0817 | -0.5061 | 1.7910 | |
| MDA-MB-157 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7879.018 | 0.0131 | -0.8224 | 1.7910 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7884.018 | 1.0389 | 1.1298 | 0.6074 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7884.018 | 0.9912 | 0.9710 | 0.6074 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7884.018 | 1.0936 | 1.3174 | 0.6074 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7884.018 | 0.6759 | 0.0494 | 0.6074 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7884.018 | 0.6993 | 0.1099 | 0.6074 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7884.018 | 0.6675 | 0.0280 | 0.6074 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7884.018 | 0.6688 | 0.0313 | 0.6074 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7884.018 | 0.5397 | -0.2754 | 0.6074 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7884.018 | 0.0942 | -0.9591 | 0.6074 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7885.042 | 0.6697 | 0.0152 | 0.5912 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7885.042 | 0.7118 | 0.1253 | 0.5912 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7885.042 | 0.9722 | 0.9068 | 0.5912 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7885.042 | 0.9174 | 0.7287 | 0.5912 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7885.042 | 0.7578 | 0.2510 | 0.5912 |