Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14287.189 | 0.0394 | -0.4817 | 2.3947 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14287.189 | 0.0005 | -0.9166 | 2.3947 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14287.189 | 0.0017 | -0.8622 | 2.3947 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14287.189 | 0.0005 | -0.9166 | 2.3947 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14625.189 | 1.0544 | 1.0393 | 2.7202 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14625.189 | 1.0769 | 1.0552 | 2.7202 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14625.189 | 0.9678 | 0.9761 | 2.7202 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14625.189 | 1.0818 | 1.0587 | 2.7202 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14625.189 | 0.6740 | 0.7300 | 2.7202 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14625.189 | 0.0125 | -0.6003 | 2.7202 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14625.189 | 0.0011 | -0.8344 | 2.7202 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14625.189 | 0.0060 | -0.6949 | 2.7202 | |
| SUM159PT | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14625.189 | 0.0093 | -0.6415 | 2.7202 | |
| SUM229PE | TNBC | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14224.189 | 0.9578 | 0.9548 | 1.8849 | |
| SUM229PE | TNBC | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14224.189 | 0.9089 | 0.9012 | 1.8849 | |
| SUM229PE | TNBC | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14224.189 | 0.9775 | 0.9760 | 1.8849 | |
| SUM229PE | TNBC | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14224.189 | 0.9578 | 0.9547 | 1.8849 | |
| SUM229PE | TNBC | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14224.189 | 0.8997 | 0.8910 | 1.8849 | |
| SUM229PE | TNBC | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14224.189 | 0.5183 | 0.4113 | 1.8849 | |
| SUM229PE | TNBC | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14224.189 | 0.0433 | -0.6218 | 1.8849 | |
| SUM229PE | TNBC | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14224.189 | 0.0233 | -0.7278 | 1.8849 | |
| SUM229PE | TNBC | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14224.189 | 0.0260 | -0.7112 | 1.8849 | |
| SUM52PE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14290.189 | 0.9711 | 0.8914 | 0.5261 | |
| SUM52PE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14290.189 | 0.9751 | 0.9066 | 0.5261 | |
| SUM52PE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14290.189 | 1.0068 | 1.0261 | 0.5261 |