Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7837.042 | 0.6492 | 0.5492 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7837.042 | 0.3352 | 0.0481 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7837.042 | 0.1148 | -0.4436 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7837.042 | 0.0627 | -0.6109 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7837.042 | 0.1185 | -0.4331 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7837.042 | 0.1568 | -0.3310 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7837.042 | 0.3157 | 0.0116 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7837.042 | 0.1992 | -0.2294 | 1.6916 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7837.042 | 0.0163 | -0.8248 | 1.6916 | |
| HCC202 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7840.018 | 0.9742 | 0.8770 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7840.018 | 1.0095 | 1.0464 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7840.018 | 1.0109 | 1.0533 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7840.018 | 0.8382 | 0.3024 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7840.018 | 0.6280 | -0.3546 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7840.018 | 0.5933 | -0.4379 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7840.018 | 0.5915 | -0.4420 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7840.018 | 0.4395 | -0.7290 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7840.018 | 0.0596 | -0.9979 | 0.4113 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7845.018 | 0.9845 | 0.9320 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7845.018 | 1.0038 | 1.0167 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7845.018 | 1.0184 | 1.0825 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7845.018 | 0.4600 | -0.6415 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7845.018 | 0.6461 | -0.2395 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7845.018 | 0.7450 | 0.0423 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7845.018 | 0.8301 | 0.3244 | 0.4518 |