Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7845.018 | 0.7630 | 0.0991 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7845.018 | 0.0415 | -0.9983 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7848.042 | 1.0320 | 1.1572 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7848.042 | 0.8249 | 0.2587 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7848.042 | 1.0451 | 1.2240 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7848.042 | 1.0149 | 1.0722 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7848.042 | 0.7917 | 0.1404 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7848.042 | 0.8025 | 0.1781 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7848.042 | 0.8696 | 0.4290 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7848.042 | 0.8172 | 0.2306 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7848.042 | 0.0510 | -0.9984 | 0.4157 | |
| HCC3153 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7853.042 | 0.9994 | 0.9993 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7853.042 | 0.9053 | 0.8902 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7853.042 | 0.8077 | 0.7718 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7853.042 | 0.9582 | 0.9522 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7853.042 | 0.2648 | -0.0589 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7853.042 | 0.3103 | 0.0296 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7853.042 | 0.3148 | 0.0380 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7853.042 | 0.3806 | 0.1561 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7853.042 | 0.0655 | -0.5740 | 1.7624 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7854.018 | 0.9541 | 0.9251 | 1.2298 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7854.018 | 0.8392 | 0.7343 | 1.2298 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7854.018 | 0.9837 | 0.9735 | 1.2298 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7854.018 | 0.7745 | 0.6248 | 1.2298 | |
| HCC38 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7854.018 | 0.3590 | -0.1306 | 1.2298 |