Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14209.189 | 0.0125 | -0.7739 | 2.0117 | |
| HCC1954 | HER2amp | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14209.189 | 0.0118 | -0.7799 | 2.0117 | |
| HCC3153 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14131.189 | 1.0000 | 0.9999 | 1.2288 | |
| HCC3153 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14131.189 | 0.9447 | 0.9095 | 1.2288 | |
| HCC3153 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14131.189 | 0.9727 | 0.9555 | 1.2288 | |
| HCC3153 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14131.189 | 0.9894 | 0.9826 | 1.2288 | |
| HCC3153 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14131.189 | 0.9834 | 0.9730 | 1.2288 | |
| HCC3153 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14131.189 | 0.6110 | 0.3393 | 1.2288 | |
| HCC3153 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14131.189 | 0.0537 | -0.8148 | 1.2288 | |
| HCC3153 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14131.189 | 0.0228 | -0.9079 | 1.2288 | |
| HCC3153 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14131.189 | 0.0217 | -0.9115 | 1.2288 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14212.189 | 0.9282 | 0.9104 | 1.6254 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14212.189 | 0.9513 | 0.9396 | 1.6254 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14212.189 | 0.9889 | 0.9864 | 1.6254 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14212.189 | 0.9572 | 0.9469 | 1.6254 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14212.189 | 0.9693 | 0.9619 | 1.6254 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14212.189 | 0.7090 | 0.6186 | 1.6254 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14212.189 | 0.0004 | -0.9835 | 1.6254 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14212.189 | 0.0034 | -0.9392 | 1.6254 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14212.189 | 0.0129 | -0.8623 | 1.6254 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14616.189 | 1.0055 | 1.0077 | 1.4258 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14616.189 | 0.9584 | 0.9413 | 1.4258 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14616.189 | 0.9789 | 0.9703 | 1.4258 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14616.189 | 0.9255 | 0.8943 | 1.4258 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14616.189 | 0.9959 | 0.9943 | 1.4258 |