Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7834.018 | 0.9948 | 0.9945 | 1.8951 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7834.018 | 0.6936 | 0.6489 | 1.8951 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7834.018 | 0.5281 | 0.4280 | 1.8951 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7834.018 | 0.5424 | 0.4483 | 1.8951 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7834.018 | 0.5586 | 0.4709 | 1.8951 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7834.018 | 0.5183 | 0.4139 | 1.8951 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7834.018 | 0.0223 | -0.7314 | 1.8951 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7835.018 | 0.8650 | 0.5233 | 0.5326 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7835.018 | 0.8621 | 0.5135 | 0.5326 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7835.018 | 0.7158 | 0.0676 | 0.5326 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7835.018 | 0.4929 | -0.4702 | 0.5326 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7835.018 | 0.6889 | -0.0064 | 0.5326 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7835.018 | 0.9018 | 0.6471 | 0.5326 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7835.018 | 1.1176 | 1.4642 | 0.5326 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7835.018 | 0.6306 | -0.1584 | 0.5326 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7835.018 | 0.0047 | -0.9999 | 0.5326 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7836.018 | 0.9774 | 0.9582 | 1.0819 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7836.018 | 0.8314 | 0.6862 | 1.0819 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7836.018 | 0.9193 | 0.8503 | 1.0819 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7836.018 | 0.2392 | -0.4670 | 1.0819 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7836.018 | 0.1137 | -0.7320 | 1.0819 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7836.018 | 0.2228 | -0.5007 | 1.0819 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7836.018 | 0.3140 | -0.3143 | 1.0819 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7836.018 | 0.2673 | -0.4092 | 1.0819 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7836.018 | 0.0104 | -0.9706 | 1.0819 |