Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7798.018 | 1.0214 | 1.0295 | 1.4461 | |
| BT-474 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7798.018 | 0.6671 | 0.5116 | 1.4461 | |
| BT-474 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7798.018 | 0.5041 | 0.2455 | 1.4461 | |
| BT-474 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7798.018 | 0.4690 | 0.1848 | 1.4461 | |
| BT-474 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7798.018 | 0.4700 | 0.1865 | 1.4461 | |
| BT-474 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7798.018 | 0.2955 | -0.1392 | 1.4461 | |
| BT-474 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7798.018 | 0.0144 | -0.8933 | 1.4461 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7801.018 | 1.0009 | 1.0030 | 0.5913 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7801.018 | 0.9566 | 0.8555 | 0.5913 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7801.018 | 1.0184 | 1.0628 | 0.5913 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7801.018 | 0.8258 | 0.4470 | 0.5913 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7801.018 | 0.5175 | -0.3437 | 0.5913 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7801.018 | 0.4375 | -0.5059 | 0.5913 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7801.018 | 0.4695 | -0.4432 | 0.5913 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7801.018 | 0.5414 | -0.2915 | 0.5913 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7801.018 | 0.0398 | -0.9914 | 0.5913 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7803.042 | 0.9860 | 0.9900 | 2.8270 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7803.042 | 0.3511 | 0.3812 | 2.8270 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7803.042 | 0.1262 | -0.0384 | 2.8270 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7803.042 | 0.2728 | 0.2632 | 2.8270 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7803.042 | 0.1402 | -0.0019 | 2.8270 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7803.042 | 0.1324 | -0.0219 | 2.8270 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7803.042 | 0.1306 | -0.0266 | 2.8270 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7803.042 | 0.1324 | -0.0219 | 2.8270 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7803.042 | 0.0108 | -0.5972 | 2.8270 |