Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7885.042 | 0.6492 | -0.0370 | 0.5912 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7885.042 | 0.6497 | -0.0357 | 0.5912 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7885.042 | 0.4633 | -0.4557 | 0.5912 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7885.042 | 0.0799 | -0.9721 | 0.5912 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7886.042 | 0.8295 | 0.4975 | 0.6462 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7886.042 | 0.7361 | 0.2448 | 0.6462 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7886.042 | 0.7706 | 0.3363 | 0.6462 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7886.042 | 0.7759 | 0.3507 | 0.6462 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7886.042 | 0.6650 | 0.0638 | 0.6462 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7886.042 | 0.6447 | 0.0140 | 0.6462 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7886.042 | 0.6511 | 0.0295 | 0.6462 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7886.042 | 0.5361 | -0.2378 | 0.6462 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7886.042 | 0.0285 | -0.9919 | 0.6462 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7892.018 | 0.9625 | 0.9695 | 2.4903 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7892.018 | 1.0461 | 1.0366 | 2.4903 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7892.018 | 0.9452 | 0.9552 | 2.4903 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7892.018 | 0.3562 | 0.3213 | 2.4903 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7892.018 | 0.2711 | 0.1842 | 2.4903 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7892.018 | 0.2614 | 0.1668 | 2.4903 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7892.018 | 0.3110 | 0.2512 | 2.4903 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7892.018 | 0.3124 | 0.2535 | 2.4903 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7892.018 | 0.0105 | -0.6791 | 2.4903 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7893.042 | 0.8783 | 0.8893 | 2.2789 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7893.042 | 0.8746 | 0.8858 | 2.2789 | |
| MDA-MB-231 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7893.042 | 0.6455 | 0.6505 | 2.2789 |