Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7875.018 | 0.9463 | 0.9345 | 1.6565 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7875.018 | 0.7938 | 0.7397 | 1.6565 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7875.018 | 0.9696 | 0.9630 | 1.6565 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7875.018 | 0.7241 | 0.6458 | 1.6565 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7875.018 | 0.4155 | 0.1769 | 1.6565 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7875.018 | 0.3778 | 0.1112 | 1.6565 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7875.018 | 0.3403 | 0.0434 | 1.6565 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7875.018 | 0.3168 | -0.0008 | 1.6565 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7875.018 | 0.0095 | -0.8800 | 1.6565 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7876.042 | 1.0652 | 1.1186 | 1.0958 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7876.042 | 1.0315 | 1.0574 | 1.0958 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7876.042 | 0.8379 | 0.7020 | 1.0958 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7876.042 | 0.9689 | 0.9432 | 1.0958 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7876.042 | 0.3867 | -0.1595 | 1.0958 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7876.042 | 0.3915 | -0.1501 | 1.0958 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7876.042 | 0.3992 | -0.1349 | 1.0958 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7876.042 | 0.4095 | -0.1146 | 1.0958 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7876.042 | 0.0363 | -0.9030 | 1.0958 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7877.042 | 1.0504 | 1.3099 | 0.3414 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7877.042 | 0.9332 | 0.6335 | 0.3414 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7877.042 | 0.9775 | 0.8709 | 0.3414 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7877.042 | 0.4735 | -0.7762 | 0.3414 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7877.042 | 0.4828 | -0.7631 | 0.3414 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7877.042 | 0.4650 | -0.7878 | 0.3414 | |
| MDA-MB-134-VI | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7877.042 | 0.5137 | -0.7158 | 0.3414 |