Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MCF 10F	NM	-	Valproic acid	HDAC	HDAC	3000	uM	12254.143	0.7907	0.6934	1.4110
MCF 10F	NM	-	Valproic acid	HDAC	HDAC	15000	uM	12254.143	0.0128	-0.9090	1.4110
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	0.0384	uM	10817.143	0.9957	0.9946	1.5734
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	0.192	uM	10817.143	0.9654	0.9557	1.5734
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	0.96	uM	10817.143	1.0276	1.0349	1.5734
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	4.8	uM	10817.143	0.9783	0.9722	1.5734
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	24	uM	10817.143	0.9667	0.9574	1.5734
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	120	uM	10817.143	0.9979	0.9973	1.5734
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	600	uM	10817.143	0.8471	0.7998	1.5734
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	3000	uM	10817.143	0.5045	0.2948	1.5734
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	15000	uM	10817.143	0.0123	-0.8778	1.5734
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	0.0384	uM	12365.143	0.9059	0.9189	2.3865
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	0.192	uM	12365.143	0.9234	0.9343	2.3865
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	0.96	uM	12365.143	0.9634	0.9690	2.3865
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	4.8	uM	12365.143	0.9092	0.9218	2.3865
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	24	uM	12365.143	0.9359	0.9453	2.3865
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	120	uM	12365.143	0.9084	0.9211	2.3865
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	600	uM	12365.143	0.8374	0.8566	2.3865
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	3000	uM	12365.143	0.4341	0.4098	2.3865
MCF12A	NM	Basal B	Valproic acid	HDAC	HDAC	15000	uM	12365.143	0.0390	-0.4863	2.3865
MCF7	HR+	Luminal	Valproic acid	HDAC	HDAC	0.0384	uM	10997.143	1.0275	1.0864	0.6416
MCF7	HR+	Luminal	Valproic acid	HDAC	HDAC	0.192	uM	10997.143	1.0452	1.1426	0.6416
MCF7	HR+	Luminal	Valproic acid	HDAC	HDAC	0.96	uM	10997.143	0.9969	0.9902	0.6416
MCF7	HR+	Luminal	Valproic acid	HDAC	HDAC	4.8	uM	10997.143	0.9834	0.9485	0.6416
MCF7	HR+	Luminal	Valproic acid	HDAC	HDAC	24	uM	10997.143	0.9822	0.9448	0.6416

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)