Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 0.0384 | uM | 10755.143 | 0.9249 | 0.8345 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 0.192 | uM | 10755.143 | 0.8927 | 0.7639 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 0.96 | uM | 10755.143 | 0.9302 | 0.8461 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 4.8 | uM | 10755.143 | 0.8993 | 0.7784 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 24 | uM | 10755.143 | 0.9291 | 0.8436 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 120 | uM | 10755.143 | 0.9770 | 0.9492 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 600 | uM | 10755.143 | 0.8864 | 0.7501 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 3000 | uM | 10755.143 | 0.6701 | 0.2840 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 15000 | uM | 10755.143 | 0.1005 | -0.8428 | 0.9034 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 0.0384 | uM | 12070.143 | 0.9713 | 0.9401 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 0.192 | uM | 12070.143 | 1.0309 | 1.0647 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 0.96 | uM | 12070.143 | 1.0116 | 1.0242 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 4.8 | uM | 12070.143 | 0.9720 | 0.9415 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 24 | uM | 12070.143 | 0.9593 | 0.9149 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 120 | uM | 12070.143 | 1.0326 | 1.0683 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 600 | uM | 12070.143 | 0.8632 | 0.7149 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 3000 | uM | 12070.143 | 0.5161 | 0.0012 | 0.9561 | |
| CAMA-1 | HR+ | Luminal | Valproic acid | HDAC | HDAC | 15000 | uM | 12070.143 | 0.0141 | -0.9768 | 0.9561 | |
| HCC1143 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 0.0384 | uM | 12112.143 | 1.0391 | 1.0459 | 1.6893 | |
| HCC1143 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 0.192 | uM | 12112.143 | 0.9502 | 0.9405 | 1.6893 | |
| HCC1143 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 0.96 | uM | 12112.143 | 0.9971 | 0.9965 | 1.6893 | |
| HCC1143 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 4.8 | uM | 12112.143 | 1.0453 | 1.0532 | 1.6893 | |
| HCC1143 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 24 | uM | 12112.143 | 0.9621 | 0.9547 | 1.6893 | |
| HCC1143 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 120 | uM | 12112.143 | 0.9390 | 0.9269 | 1.6893 | |
| HCC1143 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 600 | uM | 12112.143 | 0.8825 | 0.8573 | 1.6893 |