Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10880.151 | 0.0625 | -0.5530 | 1.8509 | |
| AU565 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10880.151 | 0.0580 | -0.5707 | 1.8509 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10581.139 | 1.0041 | 1.0071 | 1.1488 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10581.139 | 0.8967 | 0.8188 | 1.1488 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10581.139 | 0.9953 | 0.9918 | 1.1488 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10581.139 | 0.9601 | 0.9303 | 1.1488 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 10581.139 | 0.9542 | 0.9201 | 1.1488 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 10581.139 | 0.9613 | 0.9324 | 1.1488 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 10581.139 | 0.6639 | 0.4001 | 1.1488 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 10581.139 | 0.4996 | 0.0931 | 1.1488 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 10581.139 | 0.5618 | 0.2107 | 1.1488 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11854.157 | 0.9815 | 0.9750 | 1.4808 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11854.157 | 0.9502 | 0.9322 | 1.4808 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11854.157 | 0.9703 | 0.9598 | 1.4808 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11854.157 | 1.0157 | 1.0212 | 1.4808 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 11854.157 | 0.8823 | 0.8378 | 1.4808 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 11854.157 | 0.9481 | 0.9292 | 1.4808 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 11854.157 | 0.6898 | 0.5564 | 1.4808 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 11854.157 | 0.4636 | 0.1900 | 1.4808 | |
| BT-20 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 11854.157 | 0.6553 | 0.5034 | 1.4808 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12056.157 | 0.9340 | 0.8646 | 0.9748 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12056.157 | 0.9515 | 0.9006 | 0.9748 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12056.157 | 0.9407 | 0.8784 | 0.9748 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12056.157 | 0.9947 | 0.9891 | 0.9748 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12056.157 | 0.9227 | 0.8415 | 0.9748 |