Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12056.157 | 0.8677 | 0.7291 | 0.9748 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12056.157 | 0.7902 | 0.5707 | 0.9748 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12056.157 | 0.8210 | 0.6336 | 0.9748 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12056.157 | 0.8760 | 0.7459 | 0.9748 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12178.157 | 1.0438 | 1.1611 | 0.5528 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12178.157 | 1.0617 | 1.2289 | 0.5528 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12178.157 | 0.9992 | 0.9971 | 0.5528 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12178.157 | 1.0758 | 1.2828 | 0.5528 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12178.157 | 0.9790 | 0.9245 | 0.5528 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12178.157 | 1.0010 | 1.0035 | 0.5528 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12178.157 | 0.7807 | 0.2781 | 0.5528 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12178.157 | 0.6570 | -0.0647 | 0.5528 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12178.157 | 0.5329 | -0.3595 | 0.5528 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12291.157 | 0.9646 | 0.8651 | 0.5161 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12291.157 | 0.9605 | 0.8499 | 0.5161 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12291.157 | 1.0392 | 1.1546 | 0.5161 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12291.157 | 0.9693 | 0.8826 | 0.5161 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12291.157 | 0.9423 | 0.7824 | 0.5161 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12291.157 | 0.9362 | 0.7603 | 0.5161 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12291.157 | 0.6059 | -0.2425 | 0.5161 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12291.157 | 0.5897 | -0.2813 | 0.5161 | |
| BT-474 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12291.157 | 0.6494 | -0.1335 | 0.5161 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10696.151 | 1.0085 | 1.0466 | 0.3690 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10696.151 | 0.9699 | 0.8412 | 0.3690 | |
| BT-483 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10696.151 | 0.9630 | 0.8056 | 0.3690 |