Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 3000 | uM | 12112.143 | 0.5777 | 0.4454 | 1.6893 | |
| HCC1143 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 15000 | uM | 12112.143 | 0.1875 | -0.2576 | 1.6893 | |
| HCC1187 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 0.0384 | uM | 10753.143 | 0.9617 | 0.9485 | 1.4954 | |
| HCC1187 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 0.192 | uM | 10753.143 | 0.9332 | 0.9096 | 1.4954 | |
| HCC1187 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 0.96 | uM | 10753.143 | 0.9594 | 0.9454 | 1.4954 | |
| HCC1187 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 4.8 | uM | 10753.143 | 0.9478 | 0.9296 | 1.4954 | |
| HCC1187 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 24 | uM | 10753.143 | 0.9560 | 0.9408 | 1.4954 | |
| HCC1187 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 120 | uM | 10753.143 | 0.9868 | 0.9823 | 1.4954 | |
| HCC1187 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 600 | uM | 10753.143 | 0.8666 | 0.8174 | 1.4954 | |
| HCC1187 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 3000 | uM | 10753.143 | 0.4648 | 0.1982 | 1.4954 | |
| HCC1187 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 15000 | uM | 10753.143 | 0.0728 | -0.6533 | 1.4954 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.0384 | uM | 12000.143 | 0.8951 | 0.7668 | 0.8939 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.192 | uM | 12000.143 | 0.8756 | 0.7238 | 0.8939 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.96 | uM | 12000.143 | 0.9509 | 0.8904 | 0.8939 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 4.8 | uM | 12000.143 | 0.9120 | 0.8042 | 0.8939 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 24 | uM | 12000.143 | 0.8661 | 0.7029 | 0.8939 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 120 | uM | 12000.143 | 0.9420 | 0.8707 | 0.8939 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 600 | uM | 12000.143 | 0.8901 | 0.7558 | 0.8939 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 3000 | uM | 12000.143 | 0.7846 | 0.5245 | 0.8939 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 15000 | uM | 12000.143 | 0.3109 | -0.4587 | 0.8939 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.0384 | uM | 12084.143 | 0.9149 | 0.8724 | 1.3499 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.192 | uM | 12084.143 | 0.9850 | 0.9777 | 1.3499 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.96 | uM | 12084.143 | 0.9349 | 0.9027 | 1.3499 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 4.8 | uM | 12084.143 | 0.9093 | 0.8640 | 1.3499 | |
| HCC1395 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 24 | uM | 12084.143 | 0.8926 | 0.8386 | 1.3499 |