Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Triciribine | AKT | AKT | 0.00213 | uM | 7530.074 | 0.9130 | 0.9151 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Triciribine | AKT | AKT | 0.0107 | uM | 7530.074 | 1.0219 | 1.0208 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Triciribine | AKT | AKT | 0.0533 | uM | 7530.074 | 0.9497 | 0.9514 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Triciribine | AKT | AKT | 0.267 | uM | 7530.074 | 0.8513 | 0.8521 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Triciribine | AKT | AKT | 1.33 | uM | 7530.074 | 0.1379 | -0.2227 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Triciribine | AKT | AKT | 6.67 | uM | 7530.074 | 0.4912 | 0.4249 | 2.0964 | |
| SUM149PT | TNBC | Basal B | Triciribine | AKT | AKT | 33.3 | uM | 7530.074 | 0.1765 | -0.1257 | 2.0964 | |
| SUM159PT | TNBC | Basal B | Triciribine | AKT | AKT | 0.0000853 | uM | 7531.074 | 0.9568 | 0.9730 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Triciribine | AKT | AKT | 0.000427 | uM | 7531.074 | 0.9917 | 0.9949 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Triciribine | AKT | AKT | 0.00213 | uM | 7531.074 | 0.9274 | 0.9542 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Triciribine | AKT | AKT | 0.0107 | uM | 7531.074 | 0.9092 | 0.9422 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Triciribine | AKT | AKT | 0.0533 | uM | 7531.074 | 0.7699 | 0.8454 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Triciribine | AKT | AKT | 0.267 | uM | 7531.074 | 0.7185 | 0.8065 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Triciribine | AKT | AKT | 1.33 | uM | 7531.074 | 0.6676 | 0.7661 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Triciribine | AKT | AKT | 6.67 | uM | 7531.074 | 0.5127 | 0.6283 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Triciribine | AKT | AKT | 33.3 | uM | 7531.074 | 0.3042 | 0.3865 | 3.2488 | |
| SUM185PE | TNBC | Luminal | Triciribine | AKT | AKT | 0.0000853 | uM | 7532.074 | 0.9661 | 0.9128 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Triciribine | AKT | AKT | 0.000427 | uM | 7532.074 | 0.9744 | 0.9339 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Triciribine | AKT | AKT | 0.00213 | uM | 7532.074 | 0.9889 | 0.9712 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Triciribine | AKT | AKT | 0.0107 | uM | 7532.074 | 1.0047 | 1.0122 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Triciribine | AKT | AKT | 0.0533 | uM | 7532.074 | 0.8218 | 0.5516 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Triciribine | AKT | AKT | 0.267 | uM | 7532.074 | 0.7115 | 0.2875 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Triciribine | AKT | AKT | 1.33 | uM | 7532.074 | 0.6029 | 0.0392 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Triciribine | AKT | AKT | 6.67 | uM | 7532.074 | 0.4790 | -0.2284 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Triciribine | AKT | AKT | 33.3 | uM | 7532.074 | 0.3748 | -0.4383 | 0.7728 |