Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.0533 | uM | 7483.074 | 0.7061 | 0.7976 | 3.2613 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.267 | uM | 7483.074 | 0.5405 | 0.6561 | 3.2613 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 1.33 | uM | 7483.074 | 0.4422 | 0.5572 | 3.2613 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 6.67 | uM | 7483.074 | 0.2625 | 0.3272 | 3.2613 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 33.3 | uM | 7483.074 | 0.1508 | 0.1197 | 3.2613 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.0000853 | uM | 7484.074 | 0.9940 | 0.9954 | 2.6137 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.000427 | uM | 7484.074 | 0.9858 | 0.9891 | 2.6137 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.00213 | uM | 7484.074 | 0.9913 | 0.9934 | 2.6137 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.0107 | uM | 7484.074 | 0.8107 | 0.8457 | 2.6137 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.0533 | uM | 7484.074 | 0.6997 | 0.7445 | 2.6137 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.267 | uM | 7484.074 | 0.5247 | 0.5627 | 2.6137 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 1.33 | uM | 7484.074 | 0.4336 | 0.4527 | 2.6137 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 6.67 | uM | 7484.074 | 0.2728 | 0.2167 | 2.6137 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 33.3 | uM | 7484.074 | 0.1754 | 0.0276 | 2.6137 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.0000853 | uM | 7485.074 | 0.9499 | 0.9712 | 3.5413 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.000427 | uM | 7485.074 | 0.9957 | 0.9976 | 3.5413 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.00213 | uM | 7485.074 | 0.8928 | 0.9370 | 3.5413 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.0107 | uM | 7485.074 | 0.8431 | 0.9059 | 3.5413 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.0533 | uM | 7485.074 | 0.6421 | 0.7648 | 3.5413 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 0.267 | uM | 7485.074 | 0.5428 | 0.6831 | 3.5413 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 1.33 | uM | 7485.074 | 0.4341 | 0.5801 | 3.5413 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 6.67 | uM | 7485.074 | 0.2386 | 0.3345 | 3.5413 | |
MCF 10A | NM | Basal B | Triciribine | AKT | AKT | 33.3 | uM | 7485.074 | 0.1270 | 0.1167 | 3.5413 | |
MCF 10F | NM | - | Triciribine | AKT | AKT | 0.0000853 | uM | 7487.074 | 0.7606 | 0.6493 | 1.4197 | |
MCF 10F | NM | - | Triciribine | AKT | AKT | 0.000427 | uM | 7487.074 | 0.9220 | 0.8887 | 1.4197 |