Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 10937.151 | 0.6180 | 0.4578 | 1.5219 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 10937.151 | 0.4154 | 0.1228 | 1.5219 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 10937.151 | 0.2319 | -0.2344 | 1.5219 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 10937.151 | 0.2008 | -0.3035 | 1.5219 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10578.139 | 1.1144 | 1.1362 | 1.6434 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10578.139 | 0.9807 | 0.9765 | 1.6434 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10578.139 | 1.0638 | 1.0767 | 1.6434 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10578.139 | 0.9901 | 0.9879 | 1.6434 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 10578.139 | 1.0620 | 1.0746 | 1.6434 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 10578.139 | 0.8131 | 0.7634 | 1.6434 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 10578.139 | 0.3407 | 0.0387 | 1.6434 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 10578.139 | 0.2041 | -0.2396 | 1.6434 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 10578.139 | 0.2267 | -0.1895 | 1.6434 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11850.157 | 0.8664 | 0.8676 | 2.0943 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11850.157 | 0.9417 | 0.9435 | 2.0943 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11850.157 | 0.9489 | 0.9506 | 2.0943 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11850.157 | 0.9911 | 0.9915 | 2.0943 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 11850.157 | 0.8840 | 0.8856 | 2.0943 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 11850.157 | 0.6973 | 0.6837 | 2.0943 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 11850.157 | 0.2791 | 0.0873 | 2.0943 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 11850.157 | 0.2644 | 0.0596 | 2.0943 | |
| HCC38 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 11850.157 | 0.2513 | 0.0343 | 2.0943 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10873.151 | 0.9178 | 0.8597 | 1.1786 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10873.151 | 0.9287 | 0.8783 | 1.1786 | |
| HCC70 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10873.151 | 0.9662 | 0.9426 | 1.1786 |