Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MB 157 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 0.0384 | uM | 12580.143 | 1.0928 | 1.0812 | 2.2318 | |
| MB 157 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 0.192 | uM | 12580.143 | 0.9642 | 0.9676 | 2.2318 | |
| MB 157 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 0.96 | uM | 12580.143 | 1.0298 | 1.0265 | 2.2318 | |
| MB 157 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 4.8 | uM | 12580.143 | 1.0069 | 1.0061 | 2.2318 | |
| MB 157 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 24 | uM | 12580.143 | 1.1034 | 1.0901 | 2.2318 | |
| MB 157 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 120 | uM | 12580.143 | 1.0179 | 1.0160 | 2.2318 | |
| MB 157 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 600 | uM | 12580.143 | 0.9349 | 0.9405 | 2.2318 | |
| MB 157 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 3000 | uM | 12580.143 | 0.7189 | 0.7251 | 2.2318 | |
| MB 157 | Unknown | Unknown | Valproic acid | HDAC | HDAC | 15000 | uM | 12580.143 | 0.3056 | 0.1758 | 2.2318 | |
| MCF 10A | NM | Basal B | Valproic acid | HDAC | HDAC | 0.0384 | uM | 11056.143 | 1.0119 | 1.0083 | 2.8628 | |
| MCF 10A | NM | Basal B | Valproic acid | HDAC | HDAC | 0.192 | uM | 11056.143 | 0.9686 | 0.9778 | 2.8628 | |
| MCF 10A | NM | Basal B | Valproic acid | HDAC | HDAC | 0.96 | uM | 11056.143 | 1.0931 | 1.0631 | 2.8628 | |
| MCF 10A | NM | Basal B | Valproic acid | HDAC | HDAC | 4.8 | uM | 11056.143 | 1.0196 | 1.0136 | 2.8628 | |
| MCF 10A | NM | Basal B | Valproic acid | HDAC | HDAC | 24 | uM | 11056.143 | 1.0217 | 1.0151 | 2.8628 | |
| MCF 10A | NM | Basal B | Valproic acid | HDAC | HDAC | 120 | uM | 11056.143 | 1.0292 | 1.0202 | 2.8628 | |
| MCF 10A | NM | Basal B | Valproic acid | HDAC | HDAC | 600 | uM | 11056.143 | 0.7004 | 0.7661 | 2.8628 | |
| MCF 10A | NM | Basal B | Valproic acid | HDAC | HDAC | 3000 | uM | 11056.143 | 0.2177 | 0.1742 | 2.8628 | |
| MCF 10A | NM | Basal B | Valproic acid | HDAC | HDAC | 15000 | uM | 11056.143 | 0.0080 | -0.6298 | 2.8628 | |
| MCF 10F | NM | - | Valproic acid | HDAC | HDAC | 0.0384 | uM | 12254.143 | 0.9547 | 0.9354 | 1.4110 | |
| MCF 10F | NM | - | Valproic acid | HDAC | HDAC | 0.192 | uM | 12254.143 | 0.9384 | 0.9119 | 1.4110 | |
| MCF 10F | NM | - | Valproic acid | HDAC | HDAC | 0.96 | uM | 12254.143 | 1.0698 | 1.0979 | 1.4110 | |
| MCF 10F | NM | - | Valproic acid | HDAC | HDAC | 4.8 | uM | 12254.143 | 0.9733 | 0.9619 | 1.4110 | |
| MCF 10F | NM | - | Valproic acid | HDAC | HDAC | 24 | uM | 12254.143 | 0.9606 | 0.9438 | 1.4110 | |
| MCF 10F | NM | - | Valproic acid | HDAC | HDAC | 120 | uM | 12254.143 | 0.9560 | 0.9373 | 1.4110 | |
| MCF 10F | NM | - | Valproic acid | HDAC | HDAC | 600 | uM | 12254.143 | 0.9743 | 0.9635 | 1.4110 |