Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10996.151 | 0.4719 | -0.5814 | 0.4801 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10996.151 | 0.2992 | -0.8380 | 0.4801 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12192.157 | 1.0107 | 1.0373 | 0.5774 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12192.157 | 1.1092 | 1.3930 | 0.5774 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12192.157 | 0.9436 | 0.8086 | 0.5774 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12192.157 | 1.0171 | 1.0596 | 0.5774 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12192.157 | 0.9616 | 0.8689 | 0.5774 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12192.157 | 0.8222 | 0.4249 | 0.5774 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12192.157 | 0.3204 | -0.7214 | 0.5774 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12192.157 | 0.4535 | -0.4916 | 0.5774 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12192.157 | 0.5991 | -0.1766 | 0.5774 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10577.139 | 1.0981 | 1.2133 | 0.9234 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10577.139 | 1.0402 | 1.0873 | 0.9234 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10577.139 | 1.0531 | 1.1152 | 0.9234 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10577.139 | 1.0279 | 1.0605 | 0.9234 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 10577.139 | 1.0446 | 1.0968 | 0.9234 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 10577.139 | 1.0001 | 1.0002 | 0.9234 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 10577.139 | 0.4810 | -0.0947 | 0.9234 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 10577.139 | 0.3501 | -0.3581 | 0.9234 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 10577.139 | 0.4051 | -0.2483 | 0.9234 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10937.151 | 0.9392 | 0.9193 | 1.5219 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10937.151 | 1.0889 | 1.1151 | 1.5219 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10937.151 | 0.9153 | 0.8870 | 1.5219 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10937.151 | 1.0046 | 1.0060 | 1.5219 | |
| HCC3153 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 10937.151 | 0.9285 | 0.9049 | 1.5219 |