Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7547.093 | 0.7325 | 0.5105 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7547.093 | 0.9101 | 0.8370 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7547.093 | 0.9653 | 0.9372 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 7547.093 | 0.9805 | 0.9647 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 7547.093 | 0.9961 | 0.9930 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 7547.093 | 0.9322 | 0.8772 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 7547.093 | 0.9078 | 0.8329 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 66.7 | uM | 7547.093 | 0.8999 | 0.8184 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.000171 | uM | 10420.093 | 0.9745 | 0.9103 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.000853 | uM | 10420.093 | 0.9630 | 0.8704 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.00427 | uM | 10420.093 | 0.9929 | 0.9747 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 10420.093 | 0.9771 | 0.9193 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 10420.093 | 0.9986 | 0.9951 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 10420.093 | 1.0437 | 1.1579 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 10420.093 | 0.9976 | 0.9915 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 10420.093 | 1.0058 | 1.0207 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 66.7 | uM | 10420.093 | 1.0148 | 1.0530 | 0.5629 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.000341 | uM | 10580.1 | 0.9283 | 0.8218 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.00171 | uM | 10580.1 | 0.9324 | 0.8318 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.00853 | uM | 10580.1 | 0.9443 | 0.8611 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.0427 | uM | 10580.1 | 1.0274 | 1.0690 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.213 | uM | 10580.1 | 0.9703 | 0.9257 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 1.07 | uM | 10580.1 | 0.9324 | 0.8318 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 5.33 | uM | 10580.1 | 0.9100 | 0.7766 | 0.7968 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 26.7 | uM | 10580.1 | 0.9324 | 0.8319 | 0.7968 |