Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.0213 | uM | 10418.093 | 0.9544 | 0.9076 | 0.9872 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.107 | uM | 10418.093 | 0.9875 | 0.9746 | 0.9872 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.533 | uM | 10418.093 | 0.9520 | 0.9027 | 0.9872 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 2.67 | uM | 10418.093 | 0.5654 | 0.1225 | 0.9872 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 13.3 | uM | 10418.093 | 0.2119 | -0.5847 | 0.9872 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 66.7 | uM | 10418.093 | 0.2963 | -0.4167 | 0.9872 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000341 | uM | 10578.1 | 0.9246 | 0.9055 | 1.6202 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.00171 | uM | 10578.1 | 0.9258 | 0.9070 | 1.6202 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.00853 | uM | 10578.1 | 0.9577 | 0.9473 | 1.6202 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.0427 | uM | 10578.1 | 1.0130 | 1.0161 | 1.6202 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.213 | uM | 10578.1 | 0.9879 | 0.9850 | 1.6202 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 1.07 | uM | 10578.1 | 0.9367 | 0.9209 | 1.6202 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 5.33 | uM | 10578.1 | 0.4919 | 0.2908 | 1.6202 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 26.7 | uM | 10578.1 | 0.2022 | -0.2543 | 1.6202 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 133 | uM | 10578.1 | 0.1141 | -0.4761 | 1.6202 | |
| HCC70 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7470.093 | 0.9749 | 0.9535 | 1.0798 | |
| HCC70 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7470.093 | 0.9811 | 0.9650 | 1.0798 | |
| HCC70 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7470.093 | 0.9876 | 0.9771 | 1.0798 | |
| HCC70 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7470.093 | 1.0124 | 1.0230 | 1.0798 | |
| HCC70 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.107 | uM | 7470.093 | 1.0152 | 1.0281 | 1.0798 | |
| HCC70 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.533 | uM | 7470.093 | 0.9496 | 0.9065 | 1.0798 | |
| HCC70 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 2.67 | uM | 7470.093 | 0.8183 | 0.6610 | 1.0798 | |
| HCC70 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 13.3 | uM | 7470.093 | 0.4515 | -0.0423 | 1.0798 | |
| HCC70 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 66.7 | uM | 7470.093 | 0.5611 | 0.1711 | 1.0798 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000341 | uM | 7472.1 | 0.9363 | 0.8850 | 1.1120 |