Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.00171 | uM | 7472.1 | 1.4380 | 1.7727 | 1.1120 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.00853 | uM | 7472.1 | 1.0606 | 1.1086 | 1.1120 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.0427 | uM | 7472.1 | 1.1562 | 1.2788 | 1.1120 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.213 | uM | 7472.1 | 1.4325 | 1.7632 | 1.1120 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 1.07 | uM | 7472.1 | 0.9982 | 0.9967 | 1.1120 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 5.33 | uM | 7472.1 | 2.4009 | 3.3965 | 1.1120 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 26.7 | uM | 7472.1 | 2.2265 | 3.1082 | 1.1120 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 133 | uM | 7472.1 | 2.1773 | 3.0265 | 1.1120 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000171 | uM | 10379.093 | 0.9854 | 0.9871 | 2.2706 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000853 | uM | 10379.093 | 1.0149 | 1.0131 | 2.2706 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.00427 | uM | 10379.093 | 0.9686 | 0.9721 | 2.2706 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.0213 | uM | 10379.093 | 1.0195 | 1.0171 | 2.2706 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.107 | uM | 10379.093 | 1.0072 | 1.0064 | 2.2706 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.533 | uM | 10379.093 | 0.9330 | 0.9398 | 2.2706 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 2.67 | uM | 10379.093 | 0.6544 | 0.6593 | 2.2706 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 13.3 | uM | 10379.093 | 0.5647 | 0.5550 | 2.2706 | |
| Hs 578T | TNBC | Basal B | TPCA-1 | IKK | NFKB | 66.7 | uM | 10379.093 | 0.4746 | 0.4404 | 2.2706 | |
| LY2 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.000171 | uM | 10380.093 | 1.0281 | 1.0376 | 1.4880 | |
| LY2 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.000853 | uM | 10380.093 | 1.0963 | 1.1275 | 1.4880 | |
| LY2 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.00427 | uM | 10380.093 | 1.0426 | 1.0569 | 1.4880 | |
| LY2 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 10380.093 | 1.0238 | 1.0318 | 1.4880 | |
| LY2 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 10380.093 | 1.0633 | 1.0843 | 1.4880 | |
| LY2 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 10380.093 | 1.0331 | 1.0443 | 1.4880 | |
| LY2 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 10380.093 | 1.0103 | 1.0139 | 1.4880 | |
| LY2 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 10380.093 | 0.8254 | 0.7581 | 1.4880 |