Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.533 | uM | 7466.093 | 0.9805 | 0.9544 | 0.8543 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 2.67 | uM | 7466.093 | 0.9555 | 0.8961 | 0.8543 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 13.3 | uM | 7466.093 | 0.7788 | 0.4927 | 0.8543 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 66.7 | uM | 7466.093 | 0.7625 | 0.4560 | 0.8543 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000341 | uM | 10577.1 | 1.0198 | 1.0452 | 0.8774 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00171 | uM | 10577.1 | 1.0040 | 1.0090 | 0.8774 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00853 | uM | 10577.1 | 1.0103 | 1.0234 | 0.8774 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.0427 | uM | 10577.1 | 1.0378 | 1.0865 | 0.8774 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.213 | uM | 10577.1 | 1.0449 | 1.1027 | 0.8774 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 1.07 | uM | 10577.1 | 1.0283 | 1.0646 | 0.8774 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 5.33 | uM | 10577.1 | 0.9008 | 0.7754 | 0.8774 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 26.7 | uM | 10577.1 | 0.8621 | 0.6889 | 0.8774 | |
| HCC3153 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 133 | uM | 10577.1 | 0.7958 | 0.5416 | 0.8774 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7468.093 | 1.0219 | 1.0312 | 1.4007 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7468.093 | 0.9935 | 0.9907 | 1.4007 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7468.093 | 0.9865 | 0.9807 | 1.4007 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7468.093 | 1.0105 | 1.0149 | 1.4007 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.107 | uM | 7468.093 | 1.0154 | 1.0220 | 1.4007 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.533 | uM | 7468.093 | 0.9318 | 0.9016 | 1.4007 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 2.67 | uM | 7468.093 | 0.8666 | 0.8056 | 1.4007 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 13.3 | uM | 7468.093 | 0.2372 | -0.2840 | 1.4007 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 66.7 | uM | 7468.093 | 0.1981 | -0.3703 | 1.4007 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000171 | uM | 10418.093 | 0.9565 | 0.9119 | 0.9872 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000853 | uM | 10418.093 | 0.9908 | 0.9813 | 0.9872 | |
| HCC38 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.00427 | uM | 10418.093 | 1.0177 | 1.0358 | 0.9872 |