Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7473.065 | 0.9986 | 0.9990 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 8 | uM | 7473.065 | 0.9558 | 0.9676 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 40 | uM | 7473.065 | 0.2212 | 0.1599 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 200 | uM | 7473.065 | 0.0735 | -0.2210 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1000 | uM | 7473.065 | 0.0122 | -0.5922 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 5000 | uM | 7473.065 | 0.0031 | -0.7517 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7474.065 | 1.1446 | 1.0931 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7474.065 | 0.8381 | 0.8845 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7474.065 | 0.8258 | 0.8752 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7474.065 | 0.8866 | 0.9206 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 8 | uM | 7474.065 | 0.6456 | 0.7260 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 40 | uM | 7474.065 | 0.0933 | -0.1002 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 200 | uM | 7474.065 | 0.0173 | -0.4896 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1000 | uM | 7474.065 | 0.0087 | -0.5944 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 5000 | uM | 7474.065 | 0.0007 | -0.8230 | 2.9702 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7475.065 | 1.1712 | 1.1240 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7475.065 | 1.1824 | 1.1318 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7475.065 | 1.0902 | 1.0669 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7475.065 | 1.1015 | 1.0750 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 8 | uM | 7475.065 | 0.8011 | 0.8381 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 40 | uM | 7475.065 | 0.2413 | 0.1638 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 200 | uM | 7475.065 | 0.0192 | -0.5562 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1000 | uM | 7475.065 | 0.0334 | -0.4521 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 5000 | uM | 7475.065 | 0.0010 | -0.8577 | 2.6262 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 10379.065 | 1.0981 | 1.0852 | 2.2436 |