Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 40 | uM | 7470.065 | 0.1644 | -0.6637 | 1.0127 | |
| HCC70 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 200 | uM | 7470.065 | 0.0117 | -0.9752 | 1.0127 | |
| HCC70 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 1000 | uM | 7470.065 | 0.0135 | -0.9715 | 1.0127 | |
| HCC70 | TNBC | Basal A | Trichostatin A | HDAC | HDAC | 5000 | uM | 7470.065 | 0.0095 | -0.9798 | 1.0127 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7471.065 | 1.0834 | 1.0717 | 2.2733 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7471.065 | 0.9885 | 0.9899 | 2.2733 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7471.065 | 1.0092 | 1.0080 | 2.2733 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7471.065 | 0.9914 | 0.9924 | 2.2733 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 8 | uM | 7471.065 | 0.8674 | 0.8787 | 2.2733 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 40 | uM | 7471.065 | 0.0648 | -0.4000 | 2.2733 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 200 | uM | 7471.065 | 0.0106 | -0.7289 | 2.2733 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1000 | uM | 7471.065 | 0.0112 | -0.7225 | 2.2733 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 5000 | uM | 7471.065 | 0.0097 | -0.7402 | 2.2733 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7472.065 | 1.3059 | 1.6239 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7472.065 | 2.9067 | 4.9213 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7472.065 | 1.1742 | 1.3550 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7472.065 | 2.4302 | 3.9355 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 8 | uM | 7472.065 | 1.7151 | 2.4623 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 40 | uM | 7472.065 | 0.5213 | 0.0310 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 200 | uM | 7472.065 | 0.0838 | -0.8395 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 1000 | uM | 7472.065 | 0.0138 | -0.9743 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 5000 | uM | 7472.065 | 0.0021 | -0.9962 | 0.9830 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7473.065 | 1.0378 | 1.0270 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7473.065 | 1.0957 | 1.0671 | 2.7686 | |
| Hs 578T | TNBC | Basal B | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7473.065 | 1.0012 | 1.0009 | 2.7686 |