Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.0427 | uM | 7542.1 | 0.9795 | 0.9688 | 1.3201 | |
| T47D | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.213 | uM | 7542.1 | 1.0255 | 1.0386 | 1.3201 | |
| T47D | HR+ | Luminal | TPCA-1 | IKK | NFKB | 1.07 | uM | 7542.1 | 0.9442 | 0.9149 | 1.3201 | |
| T47D | HR+ | Luminal | TPCA-1 | IKK | NFKB | 5.33 | uM | 7542.1 | 0.8864 | 0.8254 | 1.3201 | |
| T47D | HR+ | Luminal | TPCA-1 | IKK | NFKB | 26.7 | uM | 7542.1 | 0.8077 | 0.7012 | 1.3201 | |
| T47D | HR+ | Luminal | TPCA-1 | IKK | NFKB | 133 | uM | 7542.1 | 0.7463 | 0.6024 | 1.3201 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7544.093 | 0.9772 | 0.9631 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7544.093 | 0.9611 | 0.9369 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7544.093 | 0.9262 | 0.8799 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7544.093 | 1.0407 | 1.0655 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.107 | uM | 7544.093 | 1.0454 | 1.0729 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.533 | uM | 7544.093 | 1.0068 | 1.0109 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 2.67 | uM | 7544.093 | 1.0546 | 1.0877 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 13.3 | uM | 7544.093 | 0.9429 | 0.9073 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 66.7 | uM | 7544.093 | 0.9462 | 0.9126 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.000341 | uM | 7545.1 | 0.9555 | 0.9217 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.00171 | uM | 7545.1 | 0.9426 | 0.8989 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.00853 | uM | 7545.1 | 0.9869 | 0.9770 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.0427 | uM | 7545.1 | 0.9915 | 0.9850 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 0.213 | uM | 7545.1 | 0.9790 | 0.9631 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 1.07 | uM | 7545.1 | 0.9759 | 0.9576 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 5.33 | uM | 7545.1 | 0.9948 | 0.9909 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 26.7 | uM | 7545.1 | 0.9958 | 0.9927 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | TPCA-1 | IKK | NFKB | 133 | uM | 7545.1 | 0.8446 | 0.7246 | 1.1396 | |
| UACC-812 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7547.093 | 0.8574 | 0.7409 | 1.1087 |