Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7515.065 | 0.8992 | 0.8458 | 1.3234 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7515.065 | 0.9844 | 0.9764 | 1.3234 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7515.065 | 1.0294 | 1.0442 | 1.3234 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 8 | uM | 7515.065 | 0.2399 | -0.3198 | 1.3234 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 40 | uM | 7515.065 | 0.0210 | -0.8919 | 1.3234 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 200 | uM | 7515.065 | 0.0146 | -0.9180 | 1.3234 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 1000 | uM | 7515.065 | 0.0131 | -0.9243 | 1.3234 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 5000 | uM | 7515.065 | 0.0127 | -0.9261 | 1.3234 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7516.065 | 0.9785 | 0.9673 | 1.3224 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7516.065 | 0.9296 | 0.8926 | 1.3224 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7516.065 | 0.9200 | 0.8778 | 1.3224 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7516.065 | 0.9577 | 0.9357 | 1.3224 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 8 | uM | 7516.065 | 0.3163 | -0.1626 | 1.3224 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 40 | uM | 7516.065 | 0.0191 | -0.8997 | 1.3224 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 200 | uM | 7516.065 | 0.0103 | -0.9370 | 1.3224 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 1000 | uM | 7516.065 | 0.0115 | -0.9316 | 1.3224 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 5000 | uM | 7516.065 | 0.0075 | -0.9507 | 1.3224 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 0.0128 | uM | 7517.065 | 0.9772 | 0.9696 | 1.5040 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 0.064 | uM | 7517.065 | 0.9961 | 0.9948 | 1.5040 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 0.32 | uM | 7517.065 | 1.0131 | 1.0174 | 1.5040 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 1.6 | uM | 7517.065 | 0.8926 | 0.8545 | 1.5040 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 8 | uM | 7517.065 | 0.1656 | -0.3950 | 1.5040 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 40 | uM | 7517.065 | 0.0173 | -0.8653 | 1.5040 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 200 | uM | 7517.065 | 0.0130 | -0.8887 | 1.5040 | |
| MDA-MB-453 | TNBC | Luminal | Trichostatin A | HDAC | HDAC | 1000 | uM | 7517.065 | 0.0143 | -0.8814 | 1.5040 |