Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Torkinib | 50 | uM | 15357.211 | 0.1011 | -0.3791 | 1.9588 | |||
| SUM159PT | TNBC | Basal B | Torkinib | 0.000128 | uM | 15402.211 | 0.9262 | 0.9510 | 3.0887 | |||
| SUM159PT | TNBC | Basal B | Torkinib | 0.00064 | uM | 15402.211 | 0.6830 | 0.7677 | 3.0887 | |||
| SUM159PT | TNBC | Basal B | Torkinib | 0.0032 | uM | 15402.211 | 0.5688 | 0.6660 | 3.0887 | |||
| SUM159PT | TNBC | Basal B | Torkinib | 0.016 | uM | 15402.211 | 0.3646 | 0.4427 | 3.0887 | |||
| SUM159PT | TNBC | Basal B | Torkinib | 0.08 | uM | 15402.211 | 0.2497 | 0.2763 | 3.0887 | |||
| SUM159PT | TNBC | Basal B | Torkinib | 0.4 | uM | 15402.211 | 0.1799 | 0.1478 | 3.0887 | |||
| SUM159PT | TNBC | Basal B | Torkinib | 2 | uM | 15402.211 | 0.1307 | 0.0348 | 3.0887 | |||
| SUM159PT | TNBC | Basal B | Torkinib | 10 | uM | 15402.211 | 0.1075 | -0.0287 | 3.0887 | |||
| SUM159PT | TNBC | Basal B | Torkinib | 50 | uM | 15402.211 | 0.0991 | -0.0537 | 3.0887 | |||
| SUM185PE | TNBC | Luminal | Torkinib | 0.000128 | uM | 15332.211 | 0.9951 | 0.9884 | 0.8413 | |||
| SUM185PE | TNBC | Luminal | Torkinib | 0.00064 | uM | 15332.211 | 0.9224 | 0.8169 | 0.8413 | |||
| SUM185PE | TNBC | Luminal | Torkinib | 0.0032 | uM | 15332.211 | 1.0348 | 1.0831 | 0.8413 | |||
| SUM185PE | TNBC | Luminal | Torkinib | 0.016 | uM | 15332.211 | 1.0273 | 1.0650 | 0.8413 | |||
| SUM185PE | TNBC | Luminal | Torkinib | 0.08 | uM | 15332.211 | 1.0638 | 1.1526 | 0.8413 | |||
| SUM185PE | TNBC | Luminal | Torkinib | 0.4 | uM | 15332.211 | 0.8909 | 0.7433 | 0.8413 | |||
| SUM185PE | TNBC | Luminal | Torkinib | 2 | uM | 15332.211 | 0.7109 | 0.3333 | 0.8413 | |||
| SUM185PE | TNBC | Luminal | Torkinib | 10 | uM | 15332.211 | 0.4704 | -0.1839 | 0.8413 | |||
| SUM185PE | TNBC | Luminal | Torkinib | 50 | uM | 15332.211 | 0.5029 | -0.1166 | 0.8413 | |||
| SUM190PT | HER2amp | Luminal | Torkinib | 0.000128 | uM | 15358.211 | 1.0349 | 1.0514 | 1.3504 | |||
| SUM190PT | HER2amp | Luminal | Torkinib | 0.00064 | uM | 15358.211 | 0.9927 | 0.9892 | 1.3504 | |||
| SUM190PT | HER2amp | Luminal | Torkinib | 0.0032 | uM | 15358.211 | 1.0268 | 1.0395 | 1.3504 | |||
| SUM190PT | HER2amp | Luminal | Torkinib | 0.016 | uM | 15358.211 | 0.8538 | 0.7792 | 1.3504 | |||
| SUM190PT | HER2amp | Luminal | Torkinib | 0.08 | uM | 15358.211 | 0.7644 | 0.6392 | 1.3504 | |||
| SUM190PT | HER2amp | Luminal | Torkinib | 0.4 | uM | 15358.211 | 0.4638 | 0.1323 | 1.3504 |