Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EFM-19 | HR+ | Luminal | Torkinib | 0.00064 | uM | 15296.211 | 0.4907 | 0.2057 | 1.4068 | |||
| EFM-19 | HR+ | Luminal | Torkinib | 0.0032 | uM | 15296.211 | 0.4054 | 0.0527 | 1.4068 | |||
| EFM-19 | HR+ | Luminal | Torkinib | 0.016 | uM | 15296.211 | 0.3293 | -0.0919 | 1.4068 | |||
| EFM-19 | HR+ | Luminal | Torkinib | 0.08 | uM | 15296.211 | 0.3121 | -0.1259 | 1.4068 | |||
| EFM-19 | HR+ | Luminal | Torkinib | 0.4 | uM | 15296.211 | 0.2891 | -0.1723 | 1.4068 | |||
| EFM-19 | HR+ | Luminal | Torkinib | 2 | uM | 15296.211 | 0.2522 | -0.2488 | 1.4068 | |||
| EFM-19 | HR+ | Luminal | Torkinib | 10 | uM | 15296.211 | 0.1604 | -0.4553 | 1.4068 | |||
| EFM-19 | HR+ | Luminal | Torkinib | 50 | uM | 15296.211 | 0.1519 | -0.4760 | 1.4068 | |||
| EFM-192A | HER2amp | Luminal | Torkinib | 0.000128 | uM | 15284.211 | 0.9543 | 0.8984 | 0.8976 | |||
| EFM-192A | HER2amp | Luminal | Torkinib | 0.00064 | uM | 15284.211 | 0.8594 | 0.6893 | 0.8976 | |||
| EFM-192A | HER2amp | Luminal | Torkinib | 0.0032 | uM | 15284.211 | 0.7208 | 0.3887 | 0.8976 | |||
| EFM-192A | HER2amp | Luminal | Torkinib | 0.016 | uM | 15284.211 | 0.4671 | -0.1435 | 0.8976 | |||
| EFM-192A | HER2amp | Luminal | Torkinib | 0.08 | uM | 15284.211 | 0.4142 | -0.2509 | 0.8976 | |||
| EFM-192A | HER2amp | Luminal | Torkinib | 0.4 | uM | 15284.211 | 0.3904 | -0.2987 | 0.8976 | |||
| EFM-192A | HER2amp | Luminal | Torkinib | 2 | uM | 15284.211 | 0.3731 | -0.3331 | 0.8976 | |||
| EFM-192A | HER2amp | Luminal | Torkinib | 10 | uM | 15284.211 | 0.2977 | -0.4815 | 0.8976 | |||
| EFM-192A | HER2amp | Luminal | Torkinib | 50 | uM | 15284.211 | 0.2374 | -0.5970 | 0.8976 | |||
| EFM-192B | HER2amp | Luminal | Torkinib | 0.000128 | uM | 15288.211 | 1.0032 | 1.0070 | 0.9250 | |||
| EFM-192B | HER2amp | Luminal | Torkinib | 0.00064 | uM | 15288.211 | 0.8711 | 0.7227 | 0.9250 | |||
| EFM-192B | HER2amp | Luminal | Torkinib | 0.0032 | uM | 15288.211 | 0.6059 | 0.1634 | 0.9250 | |||
| EFM-192B | HER2amp | Luminal | Torkinib | 0.016 | uM | 15288.211 | 0.3979 | -0.2614 | 0.9250 | |||
| EFM-192B | HER2amp | Luminal | Torkinib | 0.08 | uM | 15288.211 | 0.3375 | -0.3819 | 0.9250 | |||
| EFM-192B | HER2amp | Luminal | Torkinib | 0.4 | uM | 15288.211 | 0.3012 | -0.4535 | 0.9250 | |||
| EFM-192B | HER2amp | Luminal | Torkinib | 2 | uM | 15288.211 | 0.2761 | -0.5026 | 0.9250 | |||
| EFM-192B | HER2amp | Luminal | Torkinib | 10 | uM | 15288.211 | 0.1902 | -0.6676 | 0.9250 |