Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAL-148 | TNBC | - | Torkinib | 0.016 | uM | 15276.211 | 0.6275 | 0.5211 | 1.7025 | |||
| CAL-148 | TNBC | - | Torkinib | 0.08 | uM | 15276.211 | 0.3923 | 0.1544 | 1.7025 | |||
| CAL-148 | TNBC | - | Torkinib | 0.4 | uM | 15276.211 | 0.2607 | -0.0920 | 1.7025 | |||
| CAL-148 | TNBC | - | Torkinib | 2 | uM | 15276.211 | 0.1715 | -0.2901 | 1.7025 | |||
| CAL-148 | TNBC | - | Torkinib | 10 | uM | 15276.211 | 0.1666 | -0.3019 | 1.7025 | |||
| CAL-148 | TNBC | - | Torkinib | 50 | uM | 15276.211 | 0.1613 | -0.3152 | 1.7025 | |||
| CAL-85-1 | TNBC | - | Torkinib | 0.000128 | uM | 15280.211 | 0.8524 | 0.6612 | 0.8608 | |||
| CAL-85-1 | TNBC | - | Torkinib | 0.00064 | uM | 15280.211 | 0.7770 | 0.4919 | 0.8608 | |||
| CAL-85-1 | TNBC | - | Torkinib | 0.0032 | uM | 15280.211 | 0.6777 | 0.2727 | 0.8608 | |||
| CAL-85-1 | TNBC | - | Torkinib | 0.016 | uM | 15280.211 | 0.5030 | -0.0998 | 0.8608 | |||
| CAL-85-1 | TNBC | - | Torkinib | 0.08 | uM | 15280.211 | 0.4119 | -0.2862 | 0.8608 | |||
| CAL-85-1 | TNBC | - | Torkinib | 0.4 | uM | 15280.211 | 0.3209 | -0.4661 | 0.8608 | |||
| CAL-85-1 | TNBC | - | Torkinib | 2 | uM | 15280.211 | 0.2189 | -0.6576 | 0.8608 | |||
| CAL-85-1 | TNBC | - | Torkinib | 10 | uM | 15280.211 | 0.1340 | -0.8064 | 0.8608 | |||
| CAL-85-1 | TNBC | - | Torkinib | 50 | uM | 15280.211 | 0.1688 | -0.7468 | 0.8608 | |||
| CAMA-1 | HR+ | Luminal | Torkinib | 0.000128 | uM | 15348.211 | 0.9916 | 0.9775 | 0.7490 | |||
| CAMA-1 | HR+ | Luminal | Torkinib | 0.00064 | uM | 15348.211 | 0.8188 | 0.5314 | 0.7490 | |||
| CAMA-1 | HR+ | Luminal | Torkinib | 0.0032 | uM | 15348.211 | 0.7557 | 0.3760 | 0.7490 | |||
| CAMA-1 | HR+ | Luminal | Torkinib | 0.016 | uM | 15348.211 | 0.6255 | 0.0690 | 0.7490 | |||
| CAMA-1 | HR+ | Luminal | Torkinib | 0.08 | uM | 15348.211 | 0.4381 | -0.3355 | 0.7490 | |||
| CAMA-1 | HR+ | Luminal | Torkinib | 0.4 | uM | 15348.211 | 0.2892 | -0.6183 | 0.7490 | |||
| CAMA-1 | HR+ | Luminal | Torkinib | 2 | uM | 15348.211 | 0.2195 | -0.7358 | 0.7490 | |||
| CAMA-1 | HR+ | Luminal | Torkinib | 10 | uM | 15348.211 | 0.1579 | -0.8299 | 0.7490 | |||
| CAMA-1 | HR+ | Luminal | Torkinib | 50 | uM | 15348.211 | 0.1124 | -0.8919 | 0.7490 | |||
| EFM-19 | HR+ | Luminal | Torkinib | 0.000128 | uM | 15296.211 | 0.6417 | 0.4590 | 1.4068 |