Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 5.33 | uM | 11855.144 | 0.6814 | 0.0507 | 0.5961 | |
| BT-483 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 26.7 | uM | 11855.144 | 0.6571 | -0.0113 | 0.5961 | |
| BT-483 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 133 | uM | 11855.144 | 0.0070 | -0.9995 | 0.5961 | |
| BT-549 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 12305.168 | 0.9849 | 0.9879 | 2.5025 | |
| BT-549 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 12305.168 | 0.8857 | 0.9053 | 2.5025 | |
| BT-549 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 12305.168 | 0.7192 | 0.7532 | 2.5025 | |
| BT-549 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 12305.168 | 0.6074 | 0.6387 | 2.5025 | |
| BT-549 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.213 | uM | 12305.168 | 0.5857 | 0.6151 | 2.5025 | |
| BT-549 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 1.07 | uM | 12305.168 | 0.4744 | 0.4846 | 2.5025 | |
| BT-549 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 5.33 | uM | 12305.168 | 0.5238 | 0.5446 | 2.5025 | |
| BT-549 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 26.7 | uM | 12305.168 | 0.2775 | 0.1983 | 2.5025 | |
| BT-549 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 133 | uM | 12305.168 | 0.0010 | -0.8722 | 2.5025 | |
| CAMA-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 12070.144 | 0.9482 | 0.9114 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 12070.144 | 0.9475 | 0.9101 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 12070.144 | 0.8354 | 0.7159 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 12070.144 | 0.6728 | 0.4271 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.213 | uM | 12070.144 | 0.5557 | 0.2126 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 1.07 | uM | 12070.144 | 0.4460 | 0.0054 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 5.33 | uM | 12070.144 | 0.3386 | -0.2048 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 26.7 | uM | 12070.144 | 0.4016 | -0.0803 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 133 | uM | 12070.144 | 0.0157 | -0.9418 | 1.1742 | |
| HCC1143 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 12112.144 | 0.9219 | 0.9169 | 1.9163 | |
| HCC1143 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 12112.144 | 0.8518 | 0.8394 | 1.9163 | |
| HCC1143 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 12112.144 | 0.8734 | 0.8636 | 1.9163 | |
| HCC1143 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 12112.144 | 0.8053 | 0.7863 | 1.9163 |