Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10819.148 | 0.8256 | 0.8252 | 2.0950 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 11937.135 | 1.0005 | 1.0004 | 2.4451 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 11937.135 | 1.0460 | 1.0371 | 2.4451 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 11937.135 | 1.0127 | 1.0103 | 2.4451 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11937.135 | 1.0441 | 1.0356 | 2.4451 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11937.135 | 0.9606 | 0.9674 | 2.4451 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 11937.135 | 0.9840 | 0.9869 | 2.4451 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 11937.135 | 1.0278 | 1.0226 | 2.4451 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 11937.135 | 0.7950 | 0.8209 | 2.4451 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 11937.135 | 0.5200 | 0.5307 | 2.4451 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 10520.135 | 1.0455 | 1.0243 | 3.6895 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 10520.135 | 0.9138 | 0.9517 | 3.6895 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 10520.135 | 1.1522 | 1.0783 | 3.6895 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 10520.135 | 1.2030 | 1.1028 | 3.6895 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 10520.135 | 1.0991 | 1.0519 | 3.6895 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 10520.135 | 0.9624 | 0.9793 | 3.6895 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 10520.135 | 1.0152 | 1.0082 | 3.6895 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 10520.135 | 0.8585 | 0.9190 | 3.6895 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 10520.135 | 0.3373 | 0.4897 | 3.6895 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 11057.135 | 1.0225 | 1.0114 | 3.9340 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 11057.135 | 0.9904 | 0.9951 | 3.9340 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 11057.135 | 1.0451 | 1.0225 | 3.9340 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11057.135 | 1.0092 | 1.0046 | 3.9340 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11057.135 | 0.9547 | 0.9766 | 3.9340 | |
| SUM159PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 11057.135 | 1.0065 | 1.0033 | 3.9340 |