Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 10875.148 | 1.0086 | 1.0226 | 0.7605 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 10875.148 | 1.0213 | 1.0561 | 0.7605 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10875.148 | 1.0372 | 1.0983 | 0.7605 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10875.148 | 0.5107 | -0.1734 | 0.7605 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10875.148 | 0.9843 | 0.9589 | 0.7605 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10875.148 | 0.9912 | 0.9770 | 0.7605 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10875.148 | 0.7583 | 0.3901 | 0.7605 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10875.148 | 0.6561 | 0.1492 | 0.7605 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12428.135 | 0.9340 | 0.8516 | 0.8862 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12428.135 | 0.9708 | 0.9342 | 0.8862 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12428.135 | 1.0097 | 1.0218 | 0.8862 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12428.135 | 0.9801 | 0.9552 | 0.8862 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12428.135 | 0.8951 | 0.7649 | 0.8862 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12428.135 | 0.9635 | 0.9178 | 0.8862 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12428.135 | 0.9221 | 0.8251 | 0.8862 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12428.135 | 0.7617 | 0.4710 | 0.8862 | |
| SUM1315MO2 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12428.135 | 0.5538 | 0.0267 | 0.8862 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10819.148 | 1.0026 | 1.0025 | 2.0950 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 10819.148 | 0.9319 | 0.9338 | 2.0950 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 10819.148 | 0.9706 | 0.9717 | 2.0950 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10819.148 | 0.9388 | 0.9406 | 2.0950 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10819.148 | 1.0211 | 1.0200 | 2.0950 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10819.148 | 0.9868 | 0.9874 | 2.0950 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10819.148 | 1.0174 | 1.0165 | 2.0950 | |
| SUM149PT | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10819.148 | 0.9692 | 0.9704 | 2.0950 |