Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.213 | uM | 12112.144 | 0.6924 | 0.6509 | 1.9163 | |
| HCC1143 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 1.07 | uM | 12112.144 | 0.6143 | 0.5510 | 1.9163 | |
| HCC1143 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 5.33 | uM | 12112.144 | 0.5919 | 0.5211 | 1.9163 | |
| HCC1143 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 26.7 | uM | 12112.144 | 0.4550 | 0.3260 | 1.9163 | |
| HCC1143 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 133 | uM | 12112.144 | 0.0096 | -0.8230 | 1.9163 | |
| HCC1187 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 10753.144 | 0.9546 | 0.9298 | 1.3008 | |
| HCC1187 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 10753.144 | 0.9555 | 0.9313 | 1.3008 | |
| HCC1187 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 10753.144 | 0.8478 | 0.7615 | 1.3008 | |
| HCC1187 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 10753.144 | 0.7685 | 0.6334 | 1.3008 | |
| HCC1187 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.213 | uM | 10753.144 | 0.7406 | 0.5876 | 1.3008 | |
| HCC1187 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 1.07 | uM | 10753.144 | 0.6327 | 0.4067 | 1.3008 | |
| HCC1187 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 5.33 | uM | 10753.144 | 0.6003 | 0.3510 | 1.3008 | |
| HCC1187 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 26.7 | uM | 10753.144 | 0.4955 | 0.1657 | 1.3008 | |
| HCC1187 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 133 | uM | 10753.144 | 0.0016 | -0.9855 | 1.3008 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 12000.168 | 0.9618 | 0.9035 | 0.7873 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 12000.168 | 0.9331 | 0.8316 | 0.7873 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 12000.168 | 0.9954 | 0.9883 | 0.7873 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 12000.168 | 0.8945 | 0.7360 | 0.7873 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.213 | uM | 12000.168 | 0.8833 | 0.7085 | 0.7873 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 1.07 | uM | 12000.168 | 0.8269 | 0.5710 | 0.7873 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 5.33 | uM | 12000.168 | 0.8010 | 0.5088 | 0.7873 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 26.7 | uM | 12000.168 | 0.6526 | 0.1630 | 0.7873 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 133 | uM | 12000.168 | 0.0092 | -0.9948 | 0.7873 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 12084.144 | 0.9514 | 0.9333 | 1.4700 | |
| HCC1395 | TNBC | Basal B | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 12084.144 | 0.9084 | 0.8734 | 1.4700 |