Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 10693.148 | 0.9762 | 0.9471 | 0.8983 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10693.148 | 0.9916 | 0.9812 | 0.8983 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10693.148 | 0.9745 | 0.9434 | 0.8983 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10693.148 | 0.9917 | 0.9816 | 0.8983 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10693.148 | 1.0094 | 1.0209 | 0.8983 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10693.148 | 0.9880 | 0.9733 | 0.8983 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10693.148 | 0.7784 | 0.5133 | 0.8983 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 11936.135 | 0.9894 | 0.9752 | 0.8584 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 11936.135 | 0.9366 | 0.8531 | 0.8584 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 11936.135 | 1.0205 | 1.0480 | 0.8584 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11936.135 | 1.0017 | 1.0041 | 0.8584 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11936.135 | 1.0034 | 1.0079 | 0.8584 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 11936.135 | 0.9649 | 0.9184 | 0.8584 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 11936.135 | 0.9434 | 0.8689 | 0.8584 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 11936.135 | 0.8838 | 0.7320 | 0.8584 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 11936.135 | 0.7083 | 0.3382 | 0.8584 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10872.148 | 1.0517 | 1.0677 | 1.5151 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 10872.148 | 1.0588 | 1.0768 | 1.5151 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 10872.148 | 0.9373 | 0.9164 | 1.5151 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10872.148 | 1.0733 | 1.0956 | 1.5151 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10872.148 | 1.0866 | 1.1127 | 1.5151 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10872.148 | 0.9637 | 0.9518 | 1.5151 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10872.148 | 1.0383 | 1.0503 | 1.5151 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10872.148 | 0.7933 | 0.7165 | 1.5151 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10872.148 | 0.9615 | 0.9489 | 1.5151 |