Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12523.135 | 1.0227 | 1.0507 | 0.8958 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12523.135 | 1.0000 | 1.0001 | 0.8958 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12523.135 | 0.9960 | 0.9910 | 0.8958 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12523.135 | 0.9957 | 0.9904 | 0.8958 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12523.135 | 1.0438 | 1.0980 | 0.8958 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12523.135 | 1.0148 | 1.0330 | 0.8958 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12523.135 | 1.0507 | 1.1135 | 0.8958 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12523.135 | 1.0405 | 1.0906 | 0.8958 | |
| HCC1569 | HER2amp | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12523.135 | 0.9546 | 0.8989 | 0.8958 | |
| HCC1806 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12239.135 | 1.0734 | 1.0691 | 2.0860 | |
| HCC1806 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12239.135 | 1.0277 | 1.0263 | 2.0860 | |
| HCC1806 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12239.135 | 1.1076 | 1.1004 | 2.0860 | |
| HCC1806 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12239.135 | 1.0237 | 1.0226 | 2.0860 | |
| HCC1806 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12239.135 | 1.0349 | 1.0331 | 2.0860 | |
| HCC1806 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12239.135 | 1.0905 | 1.0848 | 2.0860 | |
| HCC1806 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12239.135 | 1.0511 | 1.0483 | 2.0860 | |
| HCC1806 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12239.135 | 1.0002 | 1.0002 | 2.0860 | |
| HCC1806 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12239.135 | 0.8128 | 0.8108 | 2.0860 | |
| HCC1937 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 11849.135 | 1.0098 | 1.0137 | 1.4337 | |
| HCC1937 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 11849.135 | 1.0543 | 1.0752 | 1.4337 | |
| HCC1937 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 11849.135 | 0.9573 | 0.9400 | 1.4337 | |
| HCC1937 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11849.135 | 0.9577 | 0.9406 | 1.4337 | |
| HCC1937 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11849.135 | 0.9591 | 0.9425 | 1.4337 | |
| HCC1937 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 11849.135 | 1.0396 | 1.0549 | 1.4337 | |
| HCC1937 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 11849.135 | 1.1173 | 1.1609 | 1.4337 |